A fantastic paper just out about relating the cellular microenvironment to the R2t* component of the signal relaxation constant, here. The authors did two really clever things: first they related the signal from the brain microenvironment (think, the area around individual synapses) to the Default Mode Network–a signature of resting awake cognitive activity. Second, they used the Allen Gene Brain atlas to look at the interplay between this brain imaging signal and the gene networks that define the molecular biology of the nervous system.
Definitely an important result. All of this out of the outstanding group at Washington University St. Louis that has been pushing the limits in this field.